The Expression of Toll-like Receptors in Cartilage Endplate Cells: A Role of Toll-like Receptor 2 in Pro-Inflammatory and Pro-Catabolic Gene Expression

Introduction: The vertebral cartilage endplate (CEP), crucial for intervertebral disc health, is prone to degeneration linked to chronic low back pain, disc degeneration, and Modic changes (MC). While it is known that disc cells express toll-like receptors (TLRs) that recognize pathogen- and damage-...

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Autors principals:	Tamara Mengis, Laura Bernhard, Andrea Nüesch, Irina Heggli, Nick Herger, Jan Devan, Roy Marcus, Christoph J. Laux, Florian Brunner, Mazda Farshad, Oliver Distler, Christine L. Le Maitre, Stefan Dudli
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-08-01
Col·lecció:	Cells
Matèries:	toll-like receptors cartilage endplate cells cartilage endplate disc degeneration Modic changes
Accés en línia:	https://www.mdpi.com/2073-4409/13/17/1402
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