Traumatic brain injury reduces soluble extracellular amyloid-β in mice: A methodologically novel combined microdialysis-controlled cortical impact study

Acute amyloid-β peptide (Aβ) deposition has been observed in young traumatic brain injury (TBI) patients, leading to the hypothesis that elevated extracellular Aβ levels could underlie the increased risk of dementia following TBI. However, a recent microdialysis-based study in human brain injury pat...

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Principais autores:	Katherine E. Schwetye, John R. Cirrito, Thomas J. Esparza, Christine L. Mac Donald, David M. Holtzman, David L. Brody
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2010-12-01
coleção:	Neurobiology of Disease
Assuntos:	Amyloid-beta Traumatic brain injury Microdialysis EEG Alzheimer's disease Dementia
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996110002391
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