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Olanzapine plus triple antiemetic therapy for prevention of carboplatin-induced nausea: a pooled analysis of two clinical trials

Abstract Background Chemotherapy-induced nausea and vomiting is a common adverse event of cancer treatments. Despite prophylactic antiemetic treatment, nausea remains a particular problem. We aimed to identify risk factors and clarify the usefulness of olanzapine for the control of carboplatin-induc...

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Principais autores: Suguru Kojima, Naoki Inui, Takahito Suzuki, Kazuki Tanaka, Masato Karayama, Yusuke Inoue, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Koji Nishimoto, Shun Matsuura, Dai Hashimoto, Takashi Matsui, Kazuhiro Asada, Takafumi Suda
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-10-01
coleção:BMC Cancer
Assuntos:
Antiemetic
Carboplatin
Chemotherapy-induced nausea and vomiting
Nausea
Olanzapine
Risk factor
Acesso em linha:https://doi.org/10.1186/s12885-025-14985-1
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