Enterococcus faecalis-induced bystander effect causes epigenetic alterations leading to aberrant TGF-β signaling and epithelial-mesenchymal transition

Abstract Background Enterococcus faecalis promotes colorectal cancer (CRC) in murine models through the microbiota-induced bystander effect (MIBE), but its potential to induce epigenetic changes remains unexplored. This study investigates how E. faecalis-infected macrophages induce epigenetic altera...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Lili Xu, Tianqi Li, Chunhua Ma, Yuanyuan Ju, Lin Huang, Rongrong Jing, Haibo Li, Xingmin Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Cell Communication and Signaling
Assuntos:	Enterococcus faecalis Macrophage Microbiota-induced bystander effect Epigenetic alteration Alox12 12-HETE
Acesso em linha:	https://doi.org/10.1186/s12964-026-02735-0
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!