Gal-3 Deficiency Suppresses Novosphyngobium aromaticivorans Inflammasome Activation and IL-17 Driven Autoimmune Cholangitis in Mice

Gal-3 has the role in multiple inflammatory pathways. Multiple-hit etiology of primary biliary cholangitis (PBC) and evolving immune response at various stages of the disease includes involvement of Gal-3 in PBC pathogenesis. In this study we aimed to clarify the role of Gal-3 in Novosphingobium aro...

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Bibliografiska uppgifter

Huvudupphov:	Aleksandar Arsenijevic, Jelena Milovanovic, Bojana Stojanovic, Dragana Djordjevic, Ivan Stanojevic, Nenad Jankovic, Danilo Vojvodic, Nebojsa Arsenijevic, Miodrag L. Lukic, Marija Milovanovic
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2019-06-01
Serie:	Frontiers in Immunology
Ämnen:	primary biliary cholangitis galectin-3 Novosphingobium aromaticivorans C57BL/6 mice NLRP3 galectin-3 inhibitor
Länkar:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01309/full
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