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Novel Scaffolds for Modulation of NOD2 Identified by Pharmacophore-Based Virtual Screening

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an innate immune pattern recognition receptor responsible for the recognition of bacterial peptidoglycan fragments. Given its central role in the formation of innate and adaptive immune responses, NOD2 represents a valuable tar...

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Príomhchruthaitheoirí: Samo Guzelj, Tihomir Tomašič, Žiga Jakopin
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2022-07-01
Sraith:Biomolecules
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2218-273X/12/8/1054
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