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Synthesis of Gd-DTPA Carborane-Containing Compound and Its Immobilization on Iron Oxide Nanoparticles for Potential Application in Neutron Capture Therapy

Cancer is one of the leading causes of global mortality, and its incidence is increasing annually. Neutron capture therapy (NCT) is a unique anticancer modality capable of selectively eliminating tumor cells within normal tissues. The development of accelerator-based, clinically mountable neutron so...

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Principais autores: Ilya V. Korolkov, Alexander Zaboronok, Kairat A. Izbasar, Zhangali A. Bekbol, Lana I. Lissovskaya, Alexandr V. Zibert, Rafael I. Shakirzyanov, Luiza N. Korganbayeva, Haolan Yang, Eiichi Ishikawa, Maxim V. Zdorovets
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Pharmaceutics
Fag:
neutron capture therapy
nanoparticles
iron oxide
carborane
Gd-DTPA
drug delivery
Online adgang:https://www.mdpi.com/1999-4923/16/6/797
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