Differential impact of interleukin-6 promoter gene polymorphism on hippocampal volume in antipsychotic-naïve schizophrenia patients

Background: Differential susceptibility model hypothesizes that a genotype need not be unfavorable all the time as postulated in stress-diathesis model but can be beneficial in a supportive context. Single-nucleotide polymorphism (SNP) (rs18000795) within the promoter region of interleukin-6 (IL-6)...

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Hlavní autoři: Venkataram Shivakumar, Vanteemar S. Sreeraj, Manjula Subbanna, Sunil V. Kalmady, Anekal C. Amaresha, Janardhanan C. Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramanian
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Medknow Publications 2020-01-01
Edice:Indian Journal of Psychiatry
Témata:
differential susceptibility
hippocampus
interleukin-6
rs18000795 polymorphism
schizophrenia
On-line přístup:https://journals.lww.com/10.4103/psychiatry.IndianJPsychiatry_486_19
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