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Engineering and application of LacI mutants with stringent expressions

Abstract Optimal transcriptional regulatory circuits are expected to exhibit stringent control, maintaining silence in the absence of inducers while exhibiting a broad induction dynamic range upon the addition of effectors. In the Plac/LacI pair, the promoter of the lac operon in Escherichia coli is...

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Autors principals: Jieyuan Wu, Chaoning Liang, Yufei Li, Yueting Zeng, Xu Sun, Peixia Jiang, Wei Chen, Dandan Xiong, Jian‐Ming Jin, Shuang‐Yan Tang
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2024-03-01
Col·lecció:Microbial Biotechnology
Accés en línia:https://doi.org/10.1111/1751-7915.14427
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