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Novel insecticide resistance mutations associated with variable PBO synergy in Anopheles gambiae s.l. from the Democratic Republic of Congo

Abstract Over-reliance on pyrethroid insecticides in insecticide-treated nets (ITNs) has imposed significant selection pressure for the evolution of insecticide resistance among major malaria vector species. In the Democratic Republic of Congo (DRC), the country with the second highest malaria burde...

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Uloženo v:
Hlavní autoři: Bethanie Pelloquin, Fiacre Agossa, Holly Acford-Palmer, Tiffany Clark, Sheila B. Ogoma, Miriam Williams, Narcisse Basosila, Francis Watsenga, Emery Metelo, Richard M. Oxborough, Yibayiri Osee Sanogo, Ferdinand Ntoya, Emma Collins, Sophie Moss, Charles McLoughlin, Monica Campos, Jody Phelan, Mark Rowland, Thomas Walker, Noboru Minakawa, Emile Zola Manzambi, Eric Mukomena, Susana Campino, Louisa A. Messenger
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-07-01
Edice:Scientific Reports
Témata:
Anopheles gambiae
Pyrethroid resistance
PBO synergy
Single nucleotide polymorphisms
Amplicon sequencing
Democratic Republic of Congo
On-line přístup:https://doi.org/10.1038/s41598-025-09016-9
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