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Separation-of-Function Alleles of <i>smc-5</i> Reveal Domain-Specific Defects and a Conserved Residue Critical for Genome Maintenance

The SMC-5/6 complex safeguards genome stability through the coordinated action of its core SMC proteins and associated NSE subunits. NSE-1 is a key component of the complex and is essential for DNA repair, yet it remains poorly characterized in <i>Caenorhabditis elegans</i>. To further elucidate the...

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Autori principali: Haiyan Yuan, Arome Solomon Odiba, Guiyan Liao, Ziteng Zhou, Wenxia Fang, Cheng Jin, Shaojun Li, Xihui Liu, Bin Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2025-05-01
Serie:Biomolecules
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Accesso online:https://www.mdpi.com/2218-273X/15/6/755
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