In vitro differentiation of common lymphoid progenitor cells into B cell using stromal cell free culture system

Abstract The OP9 culture system is an important in vitro model for B cell development. However, the complex nature of operations and the intrinsic variability of stromal cell functionality, which can be influenced by factors such as radiation exposure or contamination, pose considerable challenges t...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Pan Yang, Xiaoling Chen, Hao Wen, Meiling Yu, Haili Yu, Li Wang, Liang Gong, Lintao Zhao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-03-01
Schriftenreihe:	BMC Immunology
Schlagworte:	Vitro differentiation Common lymphoid progenitor cells B cell stromal cell free culture system
Online-Zugang:	https://doi.org/10.1186/s12865-025-00694-8
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!