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Deep learning based low-activity PET reconstruction of [11C]PiB and [18F]FE-PE2I in neurodegenerative disorders

Purpose: Positron Emission Tomography (PET) can support a diagnosis of neurodegenerative disorder by identifying disease-specific pathologies. Our aim was to investigate the feasibility of using activity reduction in clinical [18F]FE-PE2I and [11C]PiB PET/CT scans, simulating low injected activity o...

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Principais autores: Raphaël Sura Daveau, Ian Law, Otto Mølby Henriksen, Steen Gregers Hasselbalch, Ulrik Bjørn Andersen, Lasse Anderberg, Liselotte Højgaard, Flemming Littrup Andersen, Claes Nøhr Ladefoged
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-10-01
Serier:NeuroImage
Fag:
Parkinson's disease
[18F]FE-PE2I
Alzheimer's disease
[11C]PiB
Deep learning
PET denoising
Online adgang:http://www.sciencedirect.com/science/article/pii/S1053811922005298
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