Chimeric Antigen Receptors T Cell Therapy in Solid Tumor: Challenges and Clinical Applications

Adoptive cellular immunotherapy (ACT) employing engineered T lymphocytes expressing chimeric antigen receptors (CARs) has demonstrated promising antitumor effects in advanced hematologic cancers, such as relapsed or refractory acute lymphoblastic leukemia, chronic lymphocytic leukemia, and non-Hodgk...

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Bibliografische Detailangaben

Hauptverfasser:	Hamid R. Mirzaei, Analiz Rodriguez, Jennifer Shepphird, Christine E. Brown, Behnam Badie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2017-12-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	immunotherapy T cell therapy chimeric antigen receptor CAR solid tumors
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fimmu.2017.01850/full
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