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Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages

Abstract Background The circumsporozoite protein (CSP) of Plasmodium is a key surface antigen that induces antibodies and T-cells, conferring immune protection in animal models and humans. However, much of the work on CSP and immunity has been developed based on studies using rodent or non-human pri...

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Principais autores: Yevel Flores-Garcia, Sonia M. Herrera, Hugo Jhun, Daniel W. Pérez-Ramos, C. Richter King, Emily Locke, Ramadevi Raghunandan, Fidel Zavala
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-12-01
Serier:Malaria Journal
Fag:
Malaria
Transgenic parasite
Bioluminescence
Vaccine
Plasmodium falciparum
Online adgang:https://doi.org/10.1186/s12936-019-3055-9
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