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Using Magnetic Nanoparticles for Gene Transfer to Neural Stem Cells: Stem Cell Propagation Method Influences Outcomes

Genetically engineered neural stem cell (NSC) transplants offer a key strategy to augment neural repair by releasing therapeutic biomolecules into injury sites. Genetic modification of NSCs is heavily reliant on viral vectors but cytotoxic effects have prompted development of non-viral alternatives,...

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Principais autores: Mark R. Pickard, Christopher F. Adams, Perrine Barraud, Divya M. Chari
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-04-01
coleção:Journal of Functional Biomaterials
Assuntos:
nanoparticle
magnetofection
neural cell
stem cell
transplantation
genetic engineering
Acesso em linha:http://www.mdpi.com/2079-4983/6/2/259
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