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Intranasal Delivery of Darunavir-Loaded Mucoadhesive In Situ Gel: Experimental Design, In Vitro Evaluation, and Pharmacokinetic Studies

The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low perfusion of the drug to the brain. The objective of the current investigation was to design and develop an in situ mucoadhesive gel loaded with darunavir to assess the feasibility of brain targeting through...

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Furkejuvvon:
Bibliográfalaš dieđut
Váldodahkkit: Anroop B. Nair, Sunita Chaudhary, Hiral Shah, Shery Jacob, Vivek Mewada, Pottathil Shinu, Bandar Aldhubiab, Nagaraja Sreeharsha, Katharigatta N. Venugopala, Mahesh Attimarad, Jigar Shah
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-05-01
Ráidu:Gels
Fáttát:
Liŋkkat:https://www.mdpi.com/2310-2861/8/6/342
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