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Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator

Abstract WYL-domain containing transcription factors regulate fundamental processes in bacterial physiology, yet how these proteins sense cellular cues to elicit an allosteric response is not well understood. Here we describe the allosteric activation mechanism of DriD, a Caulobacter crescentus homo...

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Principais autores: Emily Cannistraci, Bindu Y. Srinivasu, Jose Chavez Orozco, Kevin Gozzi, Thomas E. Wales, Maria A. Schumacher
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-04-01
Series:Communications Biology
Acceso en liña:https://doi.org/10.1038/s42003-025-08111-x
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