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Hydrophobic residues are critical for the helix-forming, hemolytic and bactericidal activities of amphipathic antimicrobial peptide TP4.

Antimicrobial peptides are important components of the host innate defense mechanism against invading pathogens, especially for drug-resistant bacteria. In addition to bactericidal activity, the 25 residue peptide TP4 isolated from Nile tilapia also stimulates cell proliferation and regulates the in...

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Autors principals: Ting-Wei Chang, Shu-Yi Wei, Shih-Han Wang, Hung-Mu Wei, Yu-June Wang, Chiu-Feng Wang, Chinpan Chen, You-Di Liao
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2017-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC5645128?pdf=render
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