Efficacy and safety of Doxycycline versus Macrolides for Mycoplasma pneumoniae INfectiOn in Children (DOMINO): a protocol for a multicentre, randomised, open-label, superiority trial

Introduction Mycoplasma pneumoniae (MP) is a major cause of community-acquired pneumonia in children. In East Asia, the prevalence of macrolide-resistant MP (MRMP) has surged, leading to treatment failures and prolonged illness. While doxycycline is an effective alternative, its use in young childre...

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Hlavní autoři:	Jungyeon Kim, Young June Choe, Sunyoung Lee, Ki Wook Yun, Hyunju Lee, Ye Ji Kim, Ye Kyung Kim, Youn Young Choi, Changmin Kang, Young Yoo, Areum Shin, Doo Ri Kim, Bin Ahn, Byung Wook Eun, Gahee Kim, Hyun-Mi Kang, Yoon Kyung Cho, Jae Hong Choi, Kyo Jin Jo, Kyung-Ran Kim, Taek Jin Lee, Ui Yoon Choi, Yoon Sun Yoon, Mi Sun Kang, Seon Kyeong Park, Woo Mi Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMJ Publishing Group 2026-05-01
Edice:	BMJ Open
On-line přístup:	https://bmjopen.bmj.com/content/16/5/e117862.full
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