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A cluster analysis of 466 patients demonstrates that glutathione supplementation could preferentially benefit advanced unstable cirrhosis phenotype rather than stable cirrhosis

BackgroundChronic liver disease is characterized by progressive hepatic glutathione depletion and oxidative stress, yet antioxidant therapies have historically shown disappointing clinical efficacy in unselected populations. This therapeutic paradox may reflect inadequate patient stratification and...

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Auteurs principaux: Cyriac Abby Philips, Aryalakshmi Sreemohan, Ambily Baby, Arif Hussain Theruvath, Tharun Tom Oommen, Rizwan Ahamed, Ajit Tharakan, Philip Augustine
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2026-06-01
Collection:Frontiers in Pharmacology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fphar.2026.1767206/full
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