Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus

SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis. This study examined the relationships between se...

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Principais autores:	Rebecca A. Wood, Lauren Guthridge, Emma Thurmond, Carla J. Guthridge, Joseph M. Kheir, Rebecka L. Bourn, Catriona A. Wagner, Hua Chen, Wade DeJager, Susan R. Macwana, Stan Kamp, Rufei Lu, Cristina Arriens, Eliza F. Chakravarty, Aikaterini Thanou, Joan T. Merrill, Joel M. Guthridge, Judith A. James
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2021-01-01
Series:	Journal of Translational Autoimmunity
Assuntos:	Systemic lupus erythematosus Epstein-barr virus Interferon Antibodies Disease activity
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S258990902100037X
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