KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D

Vascular endothelial growth factor-C (VEGF-C) acts primarily on endothelial cells, but also on non-vascular targets, for example in the CNS and immune system. Here we describe a novel, unique VEGF-C form in the human reproductive system produced via cleavage by kallikrein-related peptidase 3 (KLK3),...

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Principais autores:	Sawan Kumar Jha, Khushbu Rauniyar, Ewa Chronowska, Kenny Mattonet, Eunice Wairimu Maina, Hannu Koistinen, Ulf-Håkan Stenman, Kari Alitalo, Michael Jeltsch
格式:	Artigo
語言:	Inglês
出版:	eLife Sciences Publications Ltd 2019-05-01
叢編:	eLife
主題:	VEGF-C VEGF-D KLK3/PSA Cathepsin D kallikrein-related peptidases lymphangiogenesis
在線閱讀:	https://elifesciences.org/articles/44478
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