Flagellin co-expression potentiates mRNA vaccine-induced cytotoxic T lymphocyte responses but not anti-tumor immunity
Abstract Personalized neoantigen mRNA vaccine showed high potency to treat advanced melanoma and pancreatic cancer in recent clinical trials. Strategies to further increase its therapeutic efficacy are highly demanded. This study explored flagellin to increase model antigen ovalbumin (OVA) mRNA-indu...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Portfolio
2025-10-01
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| Col·lecció: | Scientific Reports |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1038/s41598-025-21238-5 |
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