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Attenuation of endoplasmic reticulum stress and mitochondrial injury in kidney with ischemic postconditioning application and trimetazidine treatment

<p>Abstract</p> <p>Background</p> <p>Endoplasmic reticulum (ER) and mitochondria have been implicated in the pathology of renal ischemia/reperfusion (I/R). In the present study, we investigated whether the use of ischemic postconditioning (IPostC) and trimetazidine (TMZ) separately or combined could...

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Principais autores: Mahfoudh-Boussaid Asma, Zaouali Mohamed, Hauet Thierry, Hadj-Ayed Kaouther, Miled Abdel-Hédi, Ghoul-Mazgar Sonia, Saidane-Mosbahi Dalila, Rosello-Catafau Joan, Abdennebi Hassen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-08-01
Serier:Journal of Biomedical Science
Fag:
Kidney
Ischemia-reperfusion
Ischemic postconditioning
Trimetazidine
Endoplasmic reticulum stress
Mitochondria
Online adgang:http://www.jbiomedsci.com/content/19/1/71
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