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Transcription factors in fibroblast plasticity and CAF heterogeneity

Abstract In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro-tumoral stromal microenvironment. Howeve...

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Principais autores: Roberta Melchionna, Paola Trono, Anna Di Carlo, Francesca Di Modugno, Paola Nisticò
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2023-12-01
סדרה:Journal of Experimental & Clinical Cancer Research
נושאים:
Cancer Associated fibroblasts (CAFs)
Transcription factors (TFs)
CAF activation
CAF subtypes
Fibrosis
גישה מקוונת:https://doi.org/10.1186/s13046-023-02934-4
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