Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy

ABSTRACT Background Intervertebral disc degeneration (IDD) is a type of musculoskeletal system diseases that prevail widely in human society, exerting a substantial economic burden on society. The extensive aggregation of senescent nucleus pulposus (NP) cells within the discs is a significant charac...

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Autors principals: Yijun Dong, Chuanfu Li, Shuangshuang Tu, Mingkai Liu, Kai Lv, Liqun Duan, Feng Zhang, Haiping Cai, Xi Chen, Wenzhi Zhang
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2025-06-01
Col·lecció:JOR Spine
Matèries:
autophagy
cellular senescence
intervertebral disc degeneration
metabolomics analysis
phosphatidylethanolamine
Accés en línia:https://doi.org/10.1002/jsp2.70058
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