ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling

Abstract ARID1B haploinsufficiency in humans causes Coffin-Siris syndrome, associated with developmental delay, facial dysmorphism, and intellectual disability. The role of ARID1B has been widely studied in neuronal development, but whether it also regulates stem cells remains unknown. Here, we empl...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Mingyi Zhang, Tingwei Guo, Fei Pei, Jifan Feng, Junjun Jing, Jian Xu, Takahiko Yamada, Thach-Vu Ho, Jiahui Du, Prerna Sehgal, Yang Chai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-05-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-48285-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!