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In-Silico characterisation of antiviral activities of marine fungal derivatives: Focusing on TMPRSS2 as a therapeutic target

Marine fungi represent an underexplored source of bioactive metabolites with significant antiviral potential. The enzyme TMPRSS2, which primes the SARS-CoV-2 spike protein, is a crucial target for preventing viral entry into cells. Natural TMPRSS2 inhibitors derived from marine fungi offer promising...

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Principais autores: Reji Manjunathan, Simi Sam, Vijeesh Vayyattil, Arun Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-01-01
coleção:In Silico Research in Biomedicine
Assuntos:
Marine Fungi
Molecular Docking
Molecular Dynamic Simulation
TMPRSS2
SARS-CoV-2
Norlichexanthone and Alterporriol Q
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S3050787126000144
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