Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease

Abstract REM sleep behavior disorder (RBD), is a prodromal synucleinopathy affecting a subset of Parkinson’s disease (PD) patients and associated with neuropsychiatric symptoms. This study compared the genetic profiles of 13,020 PD patients with probable RBD (PD + RBD) and 5403 without (PD-RBD) usin...

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Hlavní autoři:	Yuri L. Sosero, Karl Heilbron, Pierre Fontanillas, Lucy Norcliffe-Kaufmann, Eric Yu, Uladzislau Rudakou, Jennifer A. Ruskey, Kathryn Freeman, Farnaz Asayesh, Kajsa A. Brolin, Maria Swanberg, Huw R. Morris, Lesley Wu, Raquel Real, Lasse Pihlstrøm, Manuela Tan, Thomas Gasser, Kathrin Brockmann, Hui Liu, Michele T. M. Hu, Donald G. Grosset, Simon J. G. Lewis, John B. Kwok, Pau Pastor, Ignacio Alvarez, Matej Skorvanek, Alexandra Lackova, Miriam Ostrozovicova, Mie Rizig, 23andMe Research Team, The International Parkinson’s Disease Genomics Consortium, Lynne Krohn, Ziv Gan-Or
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-09-01
Edice:	npj Parkinson's Disease
On-line přístup:	https://doi.org/10.1038/s41531-025-01078-w
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