Cinnamomum zeylanicum Blume (Ceylon cinnamon) bark extract attenuates doxorubicin induced cardiotoxicity in Wistar rats

Anti-tumour efficacy of doxorubicin is hindered by the cumulative dose-dependent cardiotoxicity induced by reactive oxygen species during its metabolism. As Cinnamomum zeylanicum has proven antioxidant potential, objective of this study was to investigate the cardioprotective activity of Cinnamomum...

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Detalhes bibliográficos
Main Authors: Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam, Kamani Ayoma Perera Wijewardana Jayatilaka, Lakmini Kumari Boralugoda Mudduwa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2021-08-01
Colecção:Saudi Pharmaceutical Journal
Assuntos:
Doxorubicin
Cardiotoxicity
Oxidative-stress
Cinnamomum zeylanicum bark extract
Antioxidant effect
Myeloperoxidase
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1319016421001183
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