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Human papillomavirus integration perspective in small cell cervical carcinoma

Small cell cervical carcinoma (SCCC) is a rare but aggressive malignancy. Here, the authors report human papillomavirus features and genomic landscape in SCCC via high-throughput sequencing methods and identify MYC, SOX, NR4A, ANKRD and CEA family genes as HPV-integrated hotspots.

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Principais autores: Xiaoli Wang, Wenlong Jia, Mengyao Wang, Jihong Liu, Xianrong Zhou, Zhiqing Liang, Qinghua Zhang, Sixiang Long, Suolang Quzhen, Xiangchun Li, Qiang Tian, Xiong Li, Haiying Sun, Caili Zhao, Silu Meng, Ruoqi Ning, Ling Xi, Lin Wang, Shasha Zhou, Jianwei Zhang, Li Wu, Yile Chen, Aijun Liu, Yaqi Ma, Xia Zhao, Xiaodong Cheng, Qing Zhang, Xiaobing Han, Huaxiong Pan, Yuan Zhang, Lili Cao, Yiqin Wang, Shaoping Ling, Lihua Cao, Hui Xing, Chang Xu, Long Sui, Shixuan Wang, Jianfeng Zhou, Beihua Kong, Xing Xie, Gang Chen, Shuaicheng Li, Ding Ma, Shuang Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-10-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-022-33359-w
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