Ibrutinib in B-cell lymphoma: single fighter might be enough?

Abstract Background In recent years, the B cell receptor (BCR) signaling pathway has become a “hot point” because it plays a critical role in B-cell proliferation and function. Bruton’s tyrosine kinase (BTK) is overexpressed in many subtypes of B-cell lymphoma as a downstream kinase in the BCR signa...

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Principais autores:	Chao Xue, Xin Wang, Lingyan Zhang, Qingyuan Qu, Qian Zhang, Yujie Jiang
格式:	Artigo
語言:	Inglês
出版:	BMC 2020-09-01
叢編:	Cancer Cell International
主題:	B-cell lymphoma B cell receptor (BCR) signaling pathway Bruton’s tyrosine kinase (BTK) Ibrutinib Monotherapy
在線閱讀:	http://link.springer.com/article/10.1186/s12935-020-01518-y
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