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ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

Abstract Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear. The objective of this study was to explore the f...

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Principais autores: Yanlin Cao, Jianjun Li, Sujun Qiu, Songjia Ni, Yang Duan
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-11-01
Serier:Biology Direct
Fag:
Ligamentum flavum hypertrophy
ACSM5
FABP4
Lipid accumulation
Online adgang:https://doi.org/10.1186/s13062-023-00436-z
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