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BCAM (basal cell adhesion molecule) protein expression in different tumor populations

Abstract Basal Cell Adhesion Molecule (BCAM), a receptor for laminin subunit α5, plays a crucial role in the pathogenesis of various malignancies. Notably, evidence of hypermethylation at multiple immune checkpoints in patients with low BCAM expression suggests these individuals may respond favorabl...

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Autori principali: Sneha Burela, Mengni He, Ioannis P. Trontzas, Niki Gavrielatou, Kurt A. Schalper, Solomon Langermann, Dallas B. Flies, David L. Rimm, Thazin N. Aung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer 2024-08-01
Serie:Discover Oncology
Soggetti:
The basal cell adhesion molecule (BCAM)
Quantitative immunofluorescence (QIF)
Cancer biomarkers
PD-L1 expression
Therapeutic target
Accesso online:https://doi.org/10.1007/s12672-024-01244-1
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