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ASSOCIATION OF POLYMORPHISM IN PCSK9 GENE WITH LIPID PR OFILE IN RUSSIAN POPULATION

Background and aims: mutations in LDLR, APOB, PCSK9 genes determine the development of autosomal dominant forms of familial hypercholesterolemia. The PCSK9 gene encodes an enzyme involved in the metabolism of low density lipoprotein (LDL) by post-transcriptional regulation of the LDL receptors. Purp...

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Principais autores: K. S. Astrakova, E. V. Shakhtshneider, D. E. Ivanoshchuk, P. S. Orlov, Yu. I. Ragino, M. I. Voevoda
Formato: Artigo
Idioma:Russo
Publicado em: Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics 2016-06-01
coleção:Атеросклероз
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Acesso em linha:https://ateroskleroz.elpub.ru/jour/article/view/13/13
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