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Protective effect of Shenqi Wenfei Formula against lipopolysaccharide/cigarette smoke-induced COPD in Rat based on gut microbiota and network pharmacology analysis

IntroductionThe incidence of chronic obstructive pulmonary disease (COPD) appears to be increasing and evidence suggests that the intestinal flora may play a causative role in its development. Previous studies found that the Shenqi Wenfei Formula (SQWF) can regulate pyroptosis via the NLRP3/GSDMD pa...

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Principais autores: Mengyao Shi, Qian Xue, Jinghui Xie, Qinjun Yang, Jiabing Tong, Jie Zhu, Yating Gao, Xiao Ma, Di Wu, Zegeng Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-11-01
Serier:Frontiers in Microbiology
Fag:
COPD
SQWF
network pharmacology
16S rRNA sequencing
Parabacteroides
NETs
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1441015/full
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