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Krüppel-like transcription factors KLF1 and KLF2 have unique and coordinate roles in regulating embryonic erythroid precursor maturation

The Krüppel-like transcription factors KLF1 and KLF2 are essential for embryonic erythropoiesis. They can partially compensate for each other during mouse development, and coordinately regulate numerous erythroid genes, including the β-like globins. Simultaneous ablation of KLF1 and KLF2 results in...

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Principais autores: Divya S. Vinjamur, Kristen J. Wade, Safa F. Mohamad, Jack L. Haar, Stephen T. Sawyer, Joyce A. Lloyd
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2014-10-01
Serija:Haematologica
Online dostop:https://haematologica.org/article/view/7165
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