Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells

Abstract Aim Nicotinic acetylcholine receptors (nAChRs) expressed in midbrain dopaminergic (mDA) neurons modulate mDA neuronal activity. However, their expression patterns and functional roles during mDA neuronal development remain unknown. Here, we profiled the expression and function of nAChR subt...

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Detalhes bibliográficos

Principais autores:	Takeshi Kato, Kaneyasu Nishimura, Masahiro Hirao, Shun Shimohama, Kazuyuki Takata
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-09-01
Colecção:	Neuropsychopharmacology Reports
Assuntos:	dopaminergic neurons human induced pluripotent stem cells LMO3 nicotinic acetylcholine receptors
Acesso em linha:	https://doi.org/10.1002/npr2.12361
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