c-Myc alone is enough to reprogram fibroblasts into functional macrophages

Abstract Background Macrophage-based cell therapy is promising in solid tumors, but the efficient acquisition of macrophages remains a challenge. Induced pluripotent stem cell (iPSC)-induced macrophages are a valuable source, but time-consuming and costly. The application of reprogramming technologi...

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Principais autores:	Shanshan Li, Guoyu Chen, Xia Huang, Yingwen Zhang, Shuhong Shen, Haizhong Feng, Yanxin Li
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-09-01
Serija:	Journal of Hematology & Oncology
Teme:	c-Myc Fibroblast Macrophage Immunotherapy Reprogramming
Online dostop:	https://doi.org/10.1186/s13045-024-01605-x
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