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Sintilimab-associated hemophagocytic lymphohistiocytosis: a case report

Hemophagocytic lymphohistiocytosis (HLH) is a rare hematologic syndrome characterized by massive, uncontrolled cytokine release, which can lead to multiple organ failure and is associated with a high mortality rate. Recent studies have found that checkpoint inhibitors (ICIs) can induce HLH. This cas...

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Principais autores: Jie Zhi, Xin Wang, Bo Feng, Wujie Zhao, Bin Wang, Yitao Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-05-01
coleção:Frontiers in Immunology
Assuntos:
case report
checkpoint inhibitors
esophageal squamous cell carcinoma
hemophagocytic lymphohistiocytosis
multidisciplinary discussion
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1821839/full
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