Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal...

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Главные авторы:	Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2026-07-01
Серии:	Annals of Clinical and Translational Neurology
Предметы:	multiple sclerosis ocrelizumab quantitative susceptibility mapping
Online-ссылка:	https://doi.org/10.1002/acn3.70357
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