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The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases

Summary: Primary and secondary cone photoreceptor death in retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa (RP), leads to severe visual impairment and blindness. Although the cone photoreceptor protection in retinal degenerative diseases is cr...

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Principais autores: Leah Rie Varner, Taro Chaya, Yamato Maeda, Ryotaro Tsutsumi, Shanshan Zhou, Toshinori Tsujii, Daisuke Okuzaki, Takahisa Furukawa
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-04-01
Serier:iScience
Fag:
Molecular biology
Neuroscience
Molecular neuroscience
Cellular neuroscience
Cell biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224006011
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