The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

The modification of lipopolysaccharide (LPS) in Escherichia coli and Salmonella spp. is primarily controlled by the two-component system PmrAB. LPS modification allows bacteria to avoid killing by positively charged antibiotics like polymyxin B (PMB). We previously demonstrated that in uropathogenic...

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Váldodahkkit:	Melanie N. Hurst, Connor J. Beebout, Alexis Hollingsworth, Kirsten R. Guckes, Alexandria Purcell, Tomas A. Bermudez, Diamond Williams, Seth A. Reasoner, M. Stephen Trent, Maria Hadjifrangiskou
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology 2023-10-01
Ráidu:	mSphere
Fáttát:	antibiotics tolerance UPEC amino acid metabolism QseB
Liŋkkat:	https://journals.asm.org/doi/10.1128/msphere.00059-23
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