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MicroRNA-mediated gene silencing: are we close to a unifying model?

MicroRNAs (miRNAs) comprise a group of small non-coding RNA –21 nucleotides in length. They act as post-transcriptional regulators of gene expression by forming base pairing interactions with target messenger RNA (mRNA). At least 1000 miRNAs are predicted to be expressed in humans and are encoded fo...

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Bibliografische Detailangaben
Hauptverfasser: James Victoria, Wong Sybil C.K., Sharp Tyson V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: De Gruyter 2012-02-01
Schriftenreihe:Biomolecular Concepts
Schlagworte:
Online-Zugang:https://doi.org/10.1515/bmc.2011.047
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