Preclinical in vivo evaluation of a gonococcal multivalent vaccine containing antigens identified by CASS

BackgroundNeisseria gonorrhoeae, causative agent of the human sexually transmitted infection gonorrhea, is a significant global health concern because of increasing antimicrobial resistance and the lack of an effective vaccine. Recent ecological analyses have shown a reduced incidence of gonorrhea i...

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Autori principali: Shea K. Roe, Bo Zheng, Sunita Gulati, Caroline Genco, Sanjay Ram, Paola Massari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-09-01
Serie:Frontiers in Immunology
Soggetti:
gonorrhea
combination vaccine
bactericidal antibodies
protection
mouse model
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1688536/full
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