Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model

Abstract Cerebral malaria is a severe neurovascular complication of Plasmodium falciparum infection, with high mortality rates even after treatment with effective antimalarials. Limitations in current experimental models have hindered our knowledge of the disease. We developed a 3D blood-brain barri...

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Bibliografische gegevens

Hoofdauteurs:	Livia Piatti, Alina Batzilla, Fumio Nakaki, Hannah Fleckenstein, François Korbmacher, Rory K. M. Long, Daniel Schraivogel, John A. Hawkins, Tais Romero-Uruñuela, Borja López-Gutiérrez, Silvia Sanz Sender, Yannick Schwab, Lars M. Steinmetz, James Sharpe, Maria Bernabeu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Nature Portfolio 2025-08-01
Reeks:	Nature Communications
Online toegang:	https://doi.org/10.1038/s41467-025-62514-2
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