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RU486 Reverses Emotional Disorders by Influencing Astrocytes and Endoplasmic Reticulum Stress in Chronic Restraint Stress Challenged Rats

Aims: To investigate the effect of RU486 (mifepristone) on emotional disorders in chronic restraint stress-induced rats and to explore the mechanisms of that phenomenon. Methods: For this purpose, 80 healthy male Sprague Dawley rats were randomly divided into four groups: the normal group (Con group...

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Huvudupphov: Liru Dong, Songjun Wang, Yingmin Li, Ziqin Zhao, Yiwen Shen, Li Liu, Guangming Xu, Chunling Ma, Shujin Li, Xiaojing Zhang, Bin Cong
Materialtyp: Artigo
Språk:Inglês
Utgiven: Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Serie:Cellular Physiology and Biochemistry
Ämnen:
Chronic
Restraint Stress
Astrocyte
Apoptosis
RU486
Endoplasmic Reticulum (ER) Stress
Länkar:http://www.karger.com/Article/FullText/478764
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