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Antibody–Drug Conjugates (ADCs): current and future biopharmaceuticals

Abstract Antibody–drug conjugates (ADCs) represent a novel class of biopharmaceuticals comprising monoclonal antibodies covalently conjugated to cytotoxic agents via engineered chemical linkers. This combination enables targeted delivery of cytotoxic agents to tumor site through recognizing target a...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ruili Wang, Baohui Hu, Ziyu Pan, Chongxia Mo, Xin Zhao, Guojia Liu, Ping Hou, Qi Cui, Zhao Xu, Wenjia Wang, Zhaojin Yu, Lin Zhao, Miao He, Yan Wang, Chen Fu, Minjie Wei, Lifeng Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-04-01
Schriftenreihe:Journal of Hematology & Oncology
Schlagworte:
Antibody–drug conjugates
Monoclonal antibody
Cytotoxic agents
Linkers
Targeted therapy
Clinical application
Online-Zugang:https://doi.org/10.1186/s13045-025-01704-3
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