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Heterogeneous immune cell composition in patients with combined immunodeficiency

IntroductionCombined immunodeficiencies (CIDs) are a severe class of inborn errors of immunity characterized by defective T cell development and function, often accompanied by impaired humoral and natural killer (NK) cell responses. Despite their shared clinical classification, the immunological het...

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Principais autores: Jareb J. Pérez-Caraballo, Colleen M. Roark, Megan M. Dobrose, Ana Van den Rym, Aidé Tamara Staines-Boone, Yuridia Salazar-Galvez, Noemi Gomez-Hernandez, Jian Cui, Lauren E. Brown, Xin Zhen, Saul O. Lugo Reyes, Lizbeth Blancas-Galicia, Óscar de la Calle-Martín, Reem Mohammed, Rebeca Pérez de Diego, Rubén Martínez-Barricarte
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Immunology
Assuntos:
Arpc1b
Bcl10
combined immunodeficiency
cyTOF
ezrin
inborn errors of immunity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1830231/full
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